Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling
نویسندگان
چکیده
منابع مشابه
Oxygen sensing by the carotid body chemoreceptors.
Carotid bodies are sensory organs that detect changes in arterial blood oxygen, and the ensuing reflexes are critical for maintaining homeostasis during hypoxemia. During the past decade, tremendous progress has been made toward understanding the cellular mechanisms underlying oxygen sensing at the carotid body. The purpose of this minireview is to highlight some recent concepts on sensory tran...
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Airway neuroepithelial bodies sense changes in inspired O2, whereas arterial O2 levels are monitored primarily by the carotid body. Both respond to hypoxia by initiating corrective cardiorespiratory reflexes, thereby optimising gas exchange in the face of a potentially deleterious O2 supply. One unifying theme underpinning chemotransduction in these tissues is K+ channel inhibition. However, th...
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say. J Clin Endocrinol Metab 27: 973-990, 1967 16. 13. Brecher G, Cronkite EP: Morphology and enumeration of human blood platelets. J Appl Physiol 3: 365-377, 1950 14. Baumgartner HR: Eine neue Methode zur Erzengung von Thromben 17. durch gesielte uberdehnung der Gefasswant. Z Ges Exp Med 137: 227-249, 1963 15. Stemerman MB, Spaet TH, Pitlick F, Cintron J, Lejnieks I, Tiell ML: 18. The pattern ...
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ژورنال
عنوان ژورنال: Cell Metabolism
سال: 2015
ISSN: 1550-4131
DOI: 10.1016/j.cmet.2015.09.004